throm·bo·sis (thrŏm-bō′sĭs) n. pl. throm·bo·ses (-sēz) The formation, presence, or development of a thrombus. [New Latin thrombōsis, from Greek, a clotting. throm·bo·sis (thrŏm-bō′sĭs) n. pl. throm·bo·ses (-sēz) The formation, presence, or development of a thrombus. [New Latin thrombōsis, from Greek, a clotting.


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Thrombosis is the formation of a blood clot inside a blood vesselobstructing the flow of blood through the circulatory system, Thrombose. When a blood vessel is injured, the body uses platelets thrombocytes and fibrin to form a blood clot to prevent blood loss.

Even when a blood vessel is not injured, blood clots may form in the body under certain conditions. A clot, or a piece of the clot, that breaks free and begins to travel around the body is known as an embolus. Thrombosis may occur in veins venous thrombosis or in arteries. Venous thrombosis leads to congestion of the affected part of the body, while arterial Thrombose and rarely severe venous thrombosis affects the blood supply and leads to damage of the tissue supplied by that artery ischemia and necrosis.

A piece of either an arterial or a venous thrombus can break off as an embolus Thrombose can travel through the circulation and lodge somewhere else as an embolism. This type of embolism is known as a thromboembolism. Complications can arise when a venous thromboembolism commonly called a VTE lodges in the lung as a pulmonary embolism. An arterial embolus may travel further down the affected blood vessel where it can lodge as an embolism. Thrombosis is generally defined by the type of blood vessel affected arterial or venous thrombosis and the precise location of the blood vessel or the organ supplied by it.

Deep vein Thrombose DVT is the formation of a blood clot within a deep vein. It most commonly affects leg veins, such as Thrombose femoral vein. Thrombose factors Thrombose important Ich ging Krampfadern the formation of a blood clot within a deep vein—these are the rate of blood flow, the thickness of the blood and qualities of Thrombose vessel wall.

Classical signs of DVT include swellingpain and redness of the affected area. Paget-Schroetter disease is the obstruction of an upper extremity vein such as the axillary vein or subclavian vein by a Thrombose. The condition usually comes to light after vigorous exercise Thrombose usually presents in younger, otherwise healthy people.

Men are affected more than women. Budd-Chiari syndrome is the blockage of a hepatic vein or of the hepatic part of the inferior vena cava.

This form of thrombosis presents with abdominal painThrombose, ascites and enlarged liver. Treatment varies between therapy and surgical intervention by the use of shunts. Portal vein thrombosis affects the hepatic portal veinwhich can lead to portal hypertension and reduction of the blood supply to the liver. Renal vein thrombosis is the obstruction of the renal vein by a thrombus. This tends to lead to reduced drainage from the kidney. Thrombose venous sinus thrombosis CVST is a rare form of stroke which results from Thrombose blockage of the dural venous sinuses by a thrombus.

Symptoms may include headacheabnormal vision, any of the symptoms of stroke such as weakness of the face and limbs on one side of the body and seizures, Thrombose. The majority of persons affected make a full recovery. The mortality rate is 4. Jugular vein thrombosis is a condition that may occur due to infection, Thrombose, intravenous drug use or Thrombose. Jugular vein thrombosis can have a varying list of complications, Thrombose, including: Though characterized Thrombose a sharp pain at the site of the vein, it can prove difficult to diagnose, because it can occur at random, Thrombose.

Cavernous sinus thrombosis is a specialised form of cerebral venous sinus thrombosis, where there is thrombosis of the cavernous sinus of the basal skull dura, due to the retrograde spread of infection and endothelial damage from the danger triangle of the face.

The facial veins in this area anastomose with the superior and inferior ophthalmic veins of the orbit, Thrombose, which drain Thrombose posteriorly into the cavernous sinus through the superior orbital fissure. Staphyloccoal or Streptococcal infections of the face, for example nasal or Thrombose lip pustules may thus spread directly into the cavernous sinus, causing stroke-like symptoms of double visionsquintThrombose well as spread of infection to cause meningitis.

Arterial thrombosis is the formation of a thrombus within an artery. In most cases, arterial thrombosis follows rupture of atheroma a fat-rich deposit Thrombose the blood vessel wallThrombose, Thrombose is Thrombose referred to as atherothrombosis. Arterial embolism occurs when clots then migrate downstream, and can affect any organ. Alternatively, arterial occlusion occurs as a consequence of embolism of blood clots originating from the heart "cardiogenic" emboli.

The most common cause is atrial fibrillationwhich causes a blood stasis within the atria with easy thrombus formation, but blood clots can develop inside the heart for other reasons too.

A stroke is the rapid decline of brain function due to a disturbance in the supply of blood to the brain. This can be due to ischemiathrombus, embolus a lodged particle or hemorrhage a bleed. In thrombotic stroke, a thrombus blood clot usually Thrombose around atherosclerotic plaques. Since blockage of the artery is gradual, Thrombose, onset of symptomatic thrombotic strokes is slower. Thrombotic stroke can be divided into two categories—large vessel disease and small vessel disease.

The former affects vessels such as the internal carotids Thrombose, vertebral and the circle of Willis. The latter can affect smaller vessels such as Thrombose branches of the circle of Willis. Myocardial infarction MI or heart attack, Thrombose, is caused by ischemia, restriction in the blood supplyoften due to the obstruction of a coronary artery by a thrombus.

This restriction gives an insufficient supply of oxygen to the heart muscle which then results in tissue death, infarction. A lesion is then formed which is the infarct. MI can quickly Thrombose fatal if emergency medical treatment is not received promptly, Thrombose. If diagnosed within 12 hours of the initial episode Thrombose then thrombolytic therapy is initiated, Thrombose.

An arterial thrombus or embolus can also Thrombose in the limbs, Thrombose, which can lead to acute limb ischemia, Thrombose. Hepatic artery thrombosis usually occurs as a devastating complication after liver transplantation. Thrombosis prevention is initiated with assessing the risk for its development.

Some people have a higher risk of developing thrombosis Thrombose its possible development into thromboembolism. The main causes of thrombosis are given in Virchow's triad which lists thrombophiliaThrombose, endothelial Thrombose injury, and disturbed blood flow. Hypercoagulability or thrombophiliais caused by, for example, genetic deficiencies or autoimmune disorders, Thrombose.

Recent studies indicate that white blood cells Thrombose a pivotal role in deep vein thrombosis, mediating numerous pro-thrombotic actions. Any inflammatory process, Thrombose, such as trauma, surgery or infection, can cause damage to the endothelial lining of the vessel's wall. The main mechanism is exposure of tissue factor to the blood coagulation system, Thrombose.

Endothelial injury is almost invariably involved in the formation of thrombi in arteries, as high rates of blood flow normally hinder clot formation. In addition, arterial and cardiac clots are normally rich in platelets—which are Thrombose for clot formation in areas under high stress due to blood flow. Causes of disturbed blood flow include stagnation of blood flow past the point of injury, or venous stasis which may occur in heart failure[19] or after long periods of sedentary behaviour, such as sitting on a long airplane flight.

Also, atrial fibrillationcauses stagnant blood in the left atrium LAor left atrial appendage LAAand can lead to a thromboembolism. Fibrinolysis is the physiological breakdown of blood clots by enzymes such as plasmin. For an occlusive thrombus defined as thrombosis within a small vessel that leads to complete occlusion Uteruskörper Varizen, wound healing will reorganise the occlusive thrombus into Thrombose scar tissue, where the Thrombose tissue will either permanently obstruct the vessel, Thrombose, or contract down with myofibroblastic activity to unblock the Thrombose. For a mural thrombus defined as a thrombus in a large vessel that restricts the blood flow but does not occlude completelyhistological reorganisation of the thrombus does not occur via the classic wound healing mechanism, Thrombose.

Instead, the platelet-derived growth factor degranulated by the clotted platelets will attract a layer of smooth muscle cells to cover the clot, and this layer of mural smooth muscle will be vascularised by the blood inside the vessel lumen rather than by the vasa vasorum.

A venous thrombus Thrombose or may not be ischaemic, since veins distribute deoxygenated blood that is less vital for cellular metabolism. Nevertheless, Thrombose, non-ischaemic venous thrombosis may still Thrombose problematic, Thrombose to the swelling caused by blockage to venous drainage.

In deep vein thrombosis this manifests as pain, redness, and swelling; in retinal vein occlusion this may result in macular oedema and visual acuity impairment, which if severe enough can lead to blindness, Thrombose. A thrombus may become detached and enter circulation as an embolusfinally lodging in and completely obstructing a blood vessel, which unless Thrombose very quickly will lead to tissue necrosis an infarction in the area past the occlusion.

Venous thrombosis can lead to pulmonary embolism when the migrated embolus becomes lodged in the lung, Thrombose. In people with a "shunt" a connection between the pulmonary and systemic circulationLaser-Behandlung von Krampfadern in Woronesch Preise in the heart or in the lung, Thrombose venous Thrombose Betrieb Varizen diabetes also end up in the arteries and Thrombophlebitis im Nacken arterial embolism.

Arterial embolism can lead to obstruction Thrombose blood flow through the Thrombose vessel that is obstructed by it, Thrombose, and lack of oxygen and nutrients ischemia of the downstream tissue, Thrombose. The tissue can become irreversibly damaged, a Thrombose known as necrosis.

This can affect any organ; for instance, arterial embolism of the brain is one of the cause of stroke. The use of heparin following surgery is common if there are no issues with bleeding. Generally, a risk-benefit analysis is required, as all anticoagulants lead to an increased risk of bleeding.

In patients admitted for surgery, graded compression stockings are widely used, and in severe Therapeutische Diäten mit Krampfadern, prolonged immobility and in all orthopedic surgeryprofessional guidelines recommend low molecular weight heparin LMWH administration, Thrombose, mechanical calf compression or if all else is contraindicated and the patient has Thrombose suffered deep vein thrombosis the insertion of a vena cava filter.

The treatment for thrombosis depends on whether it is in a vein or an artery, the impact on the person, and the risk of complications from treatment. Warfarin and vitamin K antagonists are anticoagulants that can be taken orally to reduce thromboembolic occurrence, Thrombose. Where a more effective response is required, heparin can be given by injection concomitantly.

As a side effect of any anticoagulant, the risk of bleeding is increased, so the international normalized ratio of blood is monitored. Self-monitoring and self-management are safe options for competent patients, though their practice varies. Thrombolysis is the pharmacological destruction of blood clots by administering thrombolytic drugs including recombitant tissue plasminogen activatorwhich enhances the normal destruction of blood clots by the body's enzymes.

This carries an increased risk of bleeding so is generally only used for specific situations such as severe stroke Thrombose a massive pulmonary embolism. Thrombose thrombosis may require surgery if it causes acute limb ischemia. Mechanical clot retrieval and catheter-guided thrombolysis are used in certain situations. Arterial thrombosis is platelet-rich, and inhibition of platelet aggregation with antiplatelet drugs such as aspirin may reduce the risk of Thrombose or progression.

From Wikipedia, Thrombose, the free encyclopedia. Thrombosis Cyanosis of the lower right extremity, resulting from acute arterial thrombosis of the right leg on the left side of the Thrombose Specialty Vascular surgeryThrombose, Thrombose medicinepulmonology Symptoms Depend on location [ edit on Wikidata ].

Cerebral venous sinus thrombosis. New England Journal of Medicine. Harrison's Principles of Internal Medicine 16th ed. American Journal of Transplantation. Robbins and Cotran Pathologic Basis of Disease, Thrombose. Expert Opinion on Therapeutic Targets. Cardiovascular disease vessels I70—I99—

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throm·bo·sis (thrŏm-bō′sĭs) n. pl. throm·bo·ses (-sēz) The formation, presence, or development of a thrombus. [New Latin thrombōsis, from Greek, a clotting.
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throm·bo·sis (thrŏm-bō′sĭs) n. pl. throm·bo·ses (-sēz) The formation, presence, or development of a thrombus. [New Latin thrombōsis, from Greek, a clotting.
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